Adriana Laura Burgueño

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We explored the role of the adiponutrin (PNPLA3) nonsynonymous-rs738409 single nucleotide polymorphism (SNP) in genetic susceptibility to nonalcoholic fatty liver disease (NAFLD) and whether this SNP(More)
UNLABELLED Insulin resistance (IR) and mitochondrial dysfunction play a central role in the pathophysiology of nonalcoholic fatty liver disease (NAFLD). We hypothesized that genetic factors and(More)
OBJECTIVE To explore the contribution of gene variants and derived haplotypes of the pregnane X receptor (NR1I2) to the severity of nonalcoholic fatty liver disease (NAFLD). METHODS A total of 290(More)
BACKGROUND Altering circadian rhythmicity results in pathophysiologic changes resembling metabolic syndrome and fat accumulation. OBJECTIVE We investigated the role of gene variants and derived(More)
OBJECTIVE To evaluate the effect of losartan-an angiotensin II type 1 receptor (AT1R) antagonist- and telmisartan-an AT1R blocker with insulin-sensitizing properties-, on the hepatic expression of(More)