Adriana G. Scandurra

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BACKGROUND We conducted this study to determine whether pulse oximetry and volumetric capnography (VCap) can determine the opening and closing pressures of lungs of anesthetized morbidly obese patients. METHODS Twenty morbidly obese patients undergoing laparoscopic bariatric surgery with capnoperitoneum were studied. A lung recruitment maneuver was(More)
OBJECTIVE To test the usefulness of dead space for determining open-lung PEEP, the lowest PEEP that prevents lung collapse after a lung recruitment maneuver. DESIGN Prospective animal study. SETTING Department of Clinical Physiology, University of Uppsala, Sweden. SUBJECTS Eight lung-lavaged pigs. INTERVENTIONS Animals were ventilated using constant(More)
BACKGROUND We studied the effects that the lung recruitment maneuver (RM) and positive end-expiratory pressure (PEEP) have on the elimination of CO(2) per breath (Vtco(2,br)). METHODS In 7 healthy and 7 lung-lavaged pigs at constant ventilation, PEEP was increased from 0 to 18 cm H(2)O and then decreased to 0 in steps of 6 cm H(2)O every 10 minutes.(More)
BACKGROUND This study assessed the performance of a Functional Approximation based on a Levenberg-Marquardt Algorithm (FA-LMA) to calculate airway dead space (VD(aw)) and the slope of phase III (S(III)) from capnograms. METHODS We performed mathematical simulations to test the effect of noises on the calculation of VD(aw) and S(III). Data from ten(More)
BACKGROUND We sought to determine whether the response of pulmonary elimination of CO2 (VCO2) to a sudden increase in positive end-expiratory pressure (PEEP) could predict fluid responsiveness and serve as a noninvasive surrogate for cardiac index (CI). METHODS Fifty-two patients undergoing cardiovascular surgery were included in this study. By using a(More)
The aim of this study was to determine typical values for non-invasive volumetric capnography (VCap) parameters for healthy volunteers and anesthetized individuals. VCap was obtained by a capnograph connected to the airway opening. We prospectively studied 33 healthy volunteers 32 ± 6 years of age weighing 70 ± 13 kg at a height of 171 ± 11 cm in the supine(More)
A blood less analysis technique of the diameter variation signal at radial artery was used to evaluate the arterial disease and the cardiovascular risk in hypertensive patients. A movement transducer was used to record the wrist pulse. A radial augmentation index was proposed to quantify the magnitude of the pressure wave reflections in the aortic region.(More)