Adrian Susan Lee

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The receptor for the female hormone progesterone (PR), like that for estrogen (ER), is an important predictive marker for response to endocrine therapy in patients with breast cancer. PR exists as two isoforms, A and B. PR is important in mammary gland development and excess production of PRB is associated with breast cancer risk. Overabundance of PRA is(More)
We have transformed hamsters lung fibroblasts with two cloned, selectable markers, the widely used pSV2gpt vector and pNEO3, which confers resistance to neomycin. Analysis of DNA extracted from both individual and pooled groups of several hundred transformants reveal that in these carrier DNA-free transformation experiments, the vector DNA are found in(More)
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