Adrian Popplewell

Learn More
The properties of IgG and its subcomponents are being exploited to generate new therapeutics with selected biological activities. In this study, a series of truncated, humanized IgG1 antibodies was expressed in Chinese hamster ovary cells, to evaluate the contribution of structural components to glycosylation and function. The series includes L243 IgG1(More)
Selective targeting of tumour-endothelium has been proposed as a means of therapy. The successful exploitation of this approach will rely on the identification of suitable targets expressed specifically on the tumour-associated endothelium. In an attempt to identify novel tumour-endothelium associated targets we have used differential mRNA display to(More)
Adrian Popplewell, an associate at a multi-disciplinary engineering consultancy Ramboll Acoustics, discusses the importance of good acoustics in the design of truly fit-for-purpose 21st Century healthcare buildings, agreeing that, as Florence Nightingale wrote in 1859: "Unnecessary noise is the most cruel absence of care which can be inflicted on the sick(More)
  • 1