Adrian Loerbroks

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To examine the association between alcohol consumption, cigarette smoking, and endometrial cancer. In 1986, the Netherlands Cohort Study was initiated. A self-administered questionnaire on dietary habits and other cancer risk factors was completed by 62,573 women. Follow-up for cancer was established by record linkage to the Netherlands Cancer Registry.(More)
BACKGROUND Childhood obesity is a serious public health problem and epidemiological studies are important to identify predictive factors. It is the aim of this study to analyse factors associated with overweight/obesity in samples of German children. METHODS 35,434 five to seven year-old children (50.9% boys) participated in cross-sectional studies(More)
Genome-wide association studies have reported an association between the A-allele of rs1006737 within CACNA1C and affective disorders and schizophrenia. The aim of the present study was to investigate the relationship between rs1006737 and established and potential endophenotypes for these disorders in a population-based cohort of 3793 subjects, using an(More)
OBJECTIVE Optimal vitamin D levels are associated with reduced cardiovascular and all-cause mortality. We investigated whether optimal 25-hydroxyvitamin D (25[OH]D) is protective in individuals with the metabolic syndrome. RESEARCH DESIGN AND METHODS The Ludwigshafen Risk and Cardiovascular Health (LURIC) study is a cohort study of subjects referred for(More)
OBJECTIVE We aimed to investigate the association between nocturnal sleep duration, changes in nocturnal sleep duration and cognitive impairment in older adults. METHODS 4010 participants of a population-based cohort study provided information on nocturnal sleep duration at baseline (1991-1995) and at follow-up (2002/2003). 792 follow-up participants aged(More)
Aufgrund fehlender Routinestatistiken des Gesundheitsstatus und der medizinischen Versorgung von Asylsuchenden kommt empirischen Studien eine besondere Rolle bei der Abbildung dieser Aspekte zu. Ziel dieses Reviews ist es, die Forschungslandschaft in diesem Bereich umfassend abzubilden, empirische Erkenntnisse zu synthetisieren und prioritären(More)
OBJECTIVE Evidence suggests that vitamin D may protect against the onset of diabetes. However, the mechanisms underlying the role of vitamin D on glycaemic status are unclear and warrant further investigation. We sought to determine the relationship between serum 25-hydroxyvitamin D (25[OH]D) and glycaemic status among intermediate-to-high-risk patients(More)
INTRODUCTION Clinical pathways (CPs) are detailed longitudinal care plans delineating measures to be conducted during a patient's treatment. Although positive effects on resource consumption and quality of care have been shown, CPs are still underutilised in many clinical settings because their development and implementation are difficult. Evidence(More)
PURPOSE OF REVIEW Abundant evidence has documented inverse associations of physical activity and the risk of cardiovascular disease (CVD). However, the effects of different types of physical activity (e.g., leisure time and occupational physical activity) are still poorly understood. RECENT FINDINGS Drawing on recommended and established guidelines for(More)
BACKGROUND Chronic obstructive pulmonary disease (COPD) co-exists with depression, but important questions remain about the determinants of this association. PURPOSE We examined the association of depressive symptoms with three aspects of COPD: self-reports of physician-diagnosed COPD, chronic respiratory symptoms, and airway obstruction. METHODS We(More)