Adrian Lewis James

Learn More
OBJECTIVES/HYPOTHESIS Middle and external ear anomalies are well recognized in Down syndrome (DS, trisomy 21). Inner ear anomalies are much less frequently described. This study reviews inner ear morphology on imaging to determine the prevalence of cochlear and vestibular anomalies in children with DS. STUDY DESIGN The authors conducted a retrospective(More)
Phasic changes in respiratory period, electrodermal activity, and the vasoconstrictive peripheral pulse amplitude response, were examined in matched groups of autistic, retarded, and normal children using repeated presentation of simple visual and auditory stimuli of differing magnitudes. Analysis of response magnitudes as a function of group membership,(More)
OBJECTIVES Early presentation of congenitally deaf children for cochlear implantation is leading to surgery in younger candidates. The safety of cochlear implantation in children aged 12 months and younger is reviewed with radiologic assessment of mastoid bone anatomy and surgical outcome data. STUDY DESIGN Analysis of case records and temporal bone(More)
Tests of handedness were carried out with 34 autistic children aged from 4 years 10 months to 18 years 11 months, and with sex-, age-, and IQ-matched retardates and sex- and age-matched normals. There were no significant differences between the groups on frequency of handedness, degree of righthand usage, or degree of dominant-hand usage. There was however(More)
BACKGROUND Menière's disease is characterised by attacks of hearing loss, tinnitus and disabling vertigo. Betahistine is used by many people to reduce the frequency and severity of these attacks but there is conflicting evidence relating to its effects. OBJECTIVES The objective of this review was to assess the effects of betahistine in people with(More)
OBJECTIVE To assess whether improvements in pulmonary function and microbial pathogenic findings can be achieved by endoscopic sinus surgery in a pediatric population with cystic fibrosis. DESIGN Retrospective medical record review. SETTING Academic research. PATIENTS Forty-one patients with cystic fibrosis who had undergone endoscopic sinus surgery(More)
Phasic changes in respiratory period, electrodermal activity (EDA), the evoked cardiac response (ECR), and the vasoconstrictive peripheral pulse amplitude response (PPAR), were examined in matched groups of autistic, retarded, and normal children, using repeated presentation of simple visual and auditory stimuli. Analysis as a function of group membership(More)
INTRODUCTION Similarities between the peripheral auditory and vestibular systems suggest that children with sensorineural hearing loss (SNHL) may demonstrate associated vestibular impairments. The current study examines vestibular function in a previously reported cohort (n = 40) augmented by 113 children with profound SNHL. METHODS The current study is(More)
OBJECTIVE To investigate and compare the usefulness of preoperative magnetic resonance (MR) imaging and high-resolution temporal bone computed tomography (HRCT) in pediatric cochlear implant candidates. STUDY DESIGN Prospective. SETTING Tertiary referral center. PATIENTS A cohort of 92 pediatric patients with profound hearing. Inclusion criteria were(More)