Adrian J C van den Brule

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Data on the incidence and determinants of human papillomavirus (HPV) infection in women >30 years old are scarce. To address this, a cohort of 1610 women--15-85 years old, HPV negative, and with normal cytological results at baseline--was monitored every 6 months for an average of 4.1 years. Information on risk factors and cervical samples for cytological(More)
BACKGROUND Preparing for HPV vaccine programs, studies are needed of HPV infection in different populations. GOAL The goal was to evaluate HPV prevalence and determinants in Concordia, Argentina. STUDY DESIGN A stratified random sample of 1786 households was obtained. Consenting women aged > or =15 years were interviewed and underwent examination,(More)
Coinfection with multiple types of human papillomavirus (HPV) and its implications for the development of efficacious HPV vaccines is a subject of great interest. To describe the occurrence of concurrent infection with multiple HPV types and to determine whether genital HPV infection modifies the risk of acquiring a new HPV infection with another HPV type,(More)
Human papillomavirus (HPV) DNA testing can be used to identify women at risk of the development of cervical cancer. The cost-effectiveness of HPV screening is dependent on the type-specific HPV prevalence in the general population. The present study describes the prevalence and spectrum of high-risk HPV types found in a large real-life population-based HPV(More)
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