DISCLAIMER This paper was prepared as the result of work sponsored by the California Energy Commission (Energy Commission) and the California Environmental Protection Agency (Cal/EPA). It does not necessarily represent the views of the Energy Commission, Cal/EPA, their employees, or the State of California. The Energy Commission, Cal/EPA, the State of… (More)
Postoperative outcome is mainly influenced by ventricular function. Tests designed to identify myocardial ischemia alone will fail to detect cardiac failure and are thus inadequate as a screening test for identification of cardiac risk in noncardiac surgical patients. We find that the degree of cardiac failure is the most important predictor of morbidity… (More)
Novel intermediate oxazoline[3,2-a]pyridiniums were facilely prepared from 2-(2,2-dimethoxyethoxy)-pyridines via acid promoted intramolecular cyclization. Sequentially, the quaternary ammonium salts were treated with different nucleophiles for performing regioselective metal-free C-O and C-N bond-cleaving to afford prevalent heterocyclic structures of… (More)
Two main mechanisms can potentially explain the spread in the magni-9 tude of global warming simulated by climate models: deep ocean heat up-10 take and climate feedbacks. Here, we show that deep oceanic heat uptake 11 is a major source of spread in simulations of 21st century climate change. 12 Models with deeper baseline polar mixed layers are associated… (More)
Pre-industrial control experiments of 15 climate models are used to exam-9 ine decadal variability in the surface climate of Southern Hemisphere extra-10 tropics. We find the climate over the Southern Ocean exhibits large decadal 11 variability in all simulations, underscoring the distinctiveness of this region's 12 internal variability. In every model,… (More)
The total synthesis of dysinosin A, a novel member of the aeruginosin group of marine natural products is discussed. The stereocontrolled synthesis also confirms the proposed structure and absolute stereochemistry of the natural product.