Adrian Grek

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The Mini-Mental State Examination (MMSE) is widely used to detect dementia, but the diagnosis of dementia also depends on a decline in the level of daily functioning. Little is known about the relationship between performance on the MMSE and daily living abilities. This relationship was investigated in this study of an elderly population by comparing scores(More)
We describe two elderly patients with senile dementia who presented with the delusion that a parent had died within weeks of the actual death of a spouse. These fixed, systematized, and persistent beliefs do not correspond to the delusions of dementia or of the bereaved elderly that have been previously described. The phenomenology and implications of these(More)
The activity of isolated M4- and H4-lactate dehydrogenase isoenzymes is studied after freezing in the saline solution to -8, -9.5, -23 and -30 degrees C. It is shown that the activity of H4-lactate dehydrogenase does not change, M4-lactate dehydrogenase being partially inactivated. It is demonstrated that a reduction in the M4-LDH activity is due to the(More)
We considered whether general practitioners should examine all older patients over a certain age for cognitive impairment in screening for early dementia. We invited presentations from key experts, selectively reviewed the literature, and developed a consensus statement. The efficacy of and benefits from unselective use of cognitive testing and informant(More)
  • Adrian Grek
  • Canadian journal of psychiatry. Revue canadienne…
  • 2007
OBJECTIVE To review the risk factors for suicide in the elderly and available interventions to avert this tragedy. METHOD Systematic literature review, based on a PubMed search for studies in English. Included were randomized controlled trials (RCTs), controlled cohort studies, and case-control studies. Wherever possible, I reviewed papers dealing with(More)
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