Adrew J Ghio

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OBJECTIVE To explore the characteristic of the signal transduction in BEAS cells induced by the crocidolite fibers. METHODS The human respiratory airway epithelial cells BEAS-2B were cultured in vitro. The final 100 microg/ml crocidolite concentration and lOnM of epidermal growth factor were cocultured with BEAS-2B cells for 30 minutes and 120 minutes.(More)
Pre- and postshift spirometry was obtained on 1,113 blue collar workers employed at 35 work sites judged to have no hazardous occupational respiratory exposures on the basis of inspection visits and environmental sampling. In addition to spirometry, a standardized questionnaire was administered by trained personnel. A study population of 944 remained after(More)
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