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The location, cytology and projections of vasopressin-, oxytocin-, and neurophysin-producing neurons in the guinea pig were investigated using specific antisera against vasopressin, oxytocin or neurophysin in the unlabeled antibody enzyme immunoperoxidase method. Light microscopic examination of the neurons of the supraoptic and paraventricular nuclei shows(More)
A composition analysis of KASCADE air shower data is performed by means of unfolding the two-dimensional frequency spectrum of electron and muon numbers. Aim of the analysis is the determination of energy spectra for elemental groups representing the chemical composition of primary cosmic rays. Since such an analysis depends crucially on simulations of air(More)
We present the results of an analysis of the large-scale anisotropy of cosmic rays in the PeV range. The Rayleigh formalism is applied to the right ascension distribution of extensive air showers measured by the KASCADE (Karlsruhe Shower Core and Array Detector) experiment. The data set contains about 10 8 extensive air showers in the energy range 0.7–6(More)
The flux of cosmic-ray–induced single hadrons near sea level has been measured with the large hadron calo-rimeter of the KASCADE experiment. The measurement corroborates former results obtained with detectors of smaller size if the enlarged veto of the 304 m 2 calorimeter surface is accounted for. The program CORSIKA/ QGSJET is used to compute the(More)
The distribution of substance P-immunoreactivity (SP-IR) in the brainstem and spinal cord of normal and colchicine-pretreated cats was analysed using the peroxidase-antiperoxidase (PAP) technique. Numerous SP-IR fibers are present in the nucleus solitarius, nucleus dorsalis nervi vagi and nucleus spinalis nervi trigemini, various parts of the formatio(More)
KASCADE has been designed to measure air showers of primary cosmic-ray energies in the PeV region and to investigate the knee phenomenon in the all-particle energy spectrum. Several observations are measured simultaneously for each event by different detector systems. The experiment started to take data in 1996 and has been completed and extended since(More)
We describe the main features of the extensive air-shower array devoted to the study of cosmic-ray primaries and their interactions at primary energies 10 PeV–1 EeV which is starting operation at Forschungszentrum Karlsruhe. It exploits the existing KASCADE multi-detector facilities, and two new detectors: Grande and Piccolo, with the respective aims of(More)
The interpretation of extensive air shower (EAS) measurements depends on the comparison with EAS simulations. These calculations rely on hadronic interaction models which have to extrapolate into kinemat-ical and energy regions not covered by present-day collider experiments. Therefore, it is necessary to check the reliability of the interaction models(More)
A novel peptide hormone, atrial natriuretic factor/cardiodilatin (ANP/CDD), was recently isolated and characterized from mammalian heart. Its presence has been demonstrated in several organs that contribute to water and sodium homeostasis, such as salivary glands. This study demonstrates the presence of ANP/CDD immunoreactivity in the salt gland of Pekin(More)
Glucagon- (GLU-IR), glicentin- (GLI-IR) and dopamine-beta-hydroxylase (DBH-IR) immunoreactive neurons were mapped in the medulla oblongata of colchicine pretreated guinea pigs. Numerous GLU-IR and GLI-IR perikarya are located in the area of the nucleus ambiguus, in the adjacent formatio reticularis, and less frequently in the nucleus reticularis lateralis,(More)