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Breeding wheat for resistance to Heterodera avenae in southern Australia has been in progress for nearly 30 years and recently a number of resistant varieties have been released. Early breeding work was hampered by three factors: • a lack of appreciation of the role and extent of the problem, • inaccurate, slow screening methods, ultimately being replaced(More)
Effect of anions on thylakoid membrane fluidity as measured by rotational correlation time, order parameter (by ESR spectroscopy) and fluorescence polarization was studied. The data in the present study offer proof that Mg(2+)-induced rigidity of thylakoid membranes could be reversed by anions like bicarbonate and chloride. Anions were found to play a role(More)
Nanomedicine is an emerging and rapidly evolving field and includes the use of nanoparticles for diagnosis and therapy of a variety of diseases, as well as in regenerative medicine. In this mini-review, leaders in the field from around the globe provide a personal perspective on the development of nanomedicine. The focus lies on the translation from(More)
INTRODUCTION Tuberculosis (TB) ranks the second leading cause of death from an infectious disease worldwide. However, treatment of TB is affected by poor patient compliance due to the requirement for daily drug administration, for lengthy periods of time, often with severe drug-induced side effects. Nanomedicines have the potential to improve treatment(More)
Tafenoquine (TQ), a new synthetic analog of primaquine, has relatively poor bioavailability and associated toxicity in glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals. A microemulsion formulation of TQ (MTQ) with sizes <20 nm improved the solubility of TQ and enhanced the oral bioavailability from 55% to 99% in healthy mice (area under the(More)
Phaseolus vulgaris L. and Pisum sativum L., with sap from those indicator plants developing symptoms being tested by agar gel double-diffusion serology against antisera to EAMV and BBSV, and also to broad bean mottle, cowpea chlorotic mottle, cowpea mosaic, and peaenation mosaic viruses. Three isolates were identified as EAMV (Fig. 1) and a subsequent(More)
There is significant interest in the application of nanoparticles to deliver immunostimulatory signals to cells. We hypothesized that curdlan (immune stimulating polymer) could be conjugated to PLGA and nanoparticles from this copolymer would possess immunostimulatory activity, be non-cytotoxic and function as an effective sustained drug release system.(More)
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