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PURPOSE The aims of this study were to report the prevalence of various microvascular complications and to identify the various clinical and biochemical characteristics related to these complications in subjects with newly diagnosed type II diabetes. METHODS Of the 5999 subjects enumerated, 1414 subjects with diabetes (both known and newly diagnosed) were(More)
BACKGROUND The concordance of microalbuminuria and diabetic retinopathy (DR) has been well reported in persons with type 1 diabetes; however, for type 2 diabetes, there is paucity of data especially from population-based studies. The aim of this study was to estimate the prevalence of albuminuria (micro - and macroalbuminuria) among persons with type 2(More)
We investigate the sequence and structural properties of RNA--protein interaction sites in 211 RNA--protein chain pairs, the largest set of RNA--protein complexes analyzed to date. Statistical analysis confirms and extends earlier analyses made on smaller data sets. There are 24.6% of hydrogen bonds between RNA and protein that are nucleobase specific,(More)
PURPOSE To report the clinical profile, etiologies, treatment modalities, and outcomes for vitreous hemorrhage in patients <18 years of age in India. METHODS The medical records of patients presenting with vitreous hemorrhage between January 2000 and January 2010 were retrospectively reviewed. RESULTS A total of 261 eyes of 246 patients (201 males) were(More)
BACKGROUND Diabetic macular edema (DME) with neurosensory retinal detachment (NSD) remains an important cause of visual loss in patients with diabetes. The aim of the study was to elucidate the association of systemic and ocular risk factors with NSD in DME. METHODS In a retrospective case-control study, we reviewed clinical records of all the subjects(More)
To study the prevalence of Abnormal Sleep Patterns (ASPs), gender-wise, in subjects with type II diabetes mellitus and its influence on diabetic microangiopathies. A population-based cross-sectional survey was conducted among 1,414 patients having type II diabetes mellitus. Diabetic retinopathy was graded using stereoscopic digital fundus photography.(More)
BACKGROUND The Metabolic syndrome (MS) consists of central obesity, glucose intolerance, hyperinsulinemia, low high density lipoproteins, high triglycerides and hypertension. Different studies have observed that MS causes microvascular complications in patients with type 2 diabetes. The aim of the study was to find out the prevalence of MS in the Indian(More)
PURPOSE To assess the rate of achieving optimal metabolic control among subjects with type 2 diabetes, to elucidate the influence of suboptimal control on diabetic retinopathy (DR) and to analyze the risk factors associated with DR in the subjects with suboptimal control. MATERIAL AND METHODS A population-based, cross-sectional study was conducted in(More)
The close relationship between RNA structure and function underlines the significance of accurately predicting RNA structures from sequence information. Structural topologies such as pseudoknots are of particular interest due to their ubiquity and direct involvement in RNA function, but identifying pseudoknots is a computationally challenging problem and(More)
PURPOSE To elucidate the distribution of mean ocular perfusion pressure (MOPP) and to study the relationship between MOPP and diabetic retinopathy (DR) in a south Indian subpopulation with diabetes. METHODS This study was a population-based, cross-sectional evaluation of 1368 subjects, aged ≥40 years, with type 2 diabetes. DR was diagnosed on the basis of(More)