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Severity grading of psoriatic plaques using deep CNN based multi-task learning
- A. Pal, Akshay Chaturvedi, Utpal Garain, Aditi Chandra, R. Chatterjee
- Computer Science23rd International Conference on Pattern…
- 1 December 2016
A novel deep CNN based architecture for achieving the problem of automatic machine analysis based severity scoring of psoriasis skin disease is presented and shows that the deepCNN based architectures (both the STL and MTL) achieve promising performances.
Genetic and epigenetic basis of psoriasis pathogenesis.
Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis
- Aditi Chandra, Swapan Senapati, Sudipta Roy, G. Chatterjee, R. Chatterjee
- Medicine, BiologyClinical Epigenetics
- 9 August 2018
This study indicated the possible involvement of DNA methylation in regulating the cardinal pathophysiological features in psoriasis for the first time.
Psoriasis skin biopsy image segmentation using Deep Convolutional Neural Network
Genome-wide DNA methylation profile identified a unique set of differentially methylated immune genes in oral squamous cell carcinoma patients in India
This study identified a unique set of hypomethylated regions, enriched in the promoters of immune response genes, and indicated the presence of a strong immune component in the tumor microenvironment.
Increased Risk of Psoriasis due to combined effect of HLA-Cw6 and LCE3 risk alleles in Indian population
Integration of genetic and gene expression data allowed us to identify the actual disease variants at the LCE3 cluster among the psoriasis patients in India.
Associations of ERAP1 coding variants and domain specific interaction with HLA-C∗06 in the early onset psoriasis patients of India.
Localized TWIST1 and TWIST2 basic domain substitutions cause four distinct human diseases that can be modeled in Caenorhabditis elegans
A new clinical entity is described, Sweeney-Cox syndrome, associated with distinct de novo amino acid substitutions at a highly conserved glutamic acid residue located in the basic DNA binding domain of TWIST1, in two subjects with frontonasal dysplasia and additional malformations.
Severity Assessment of Psoriatic Plaques Using Deep CNN Based Ordinal Classification
- A. Pal, Akshay Chaturvedi, Utpal Garain, Aditi Chandra, R. Chatterjee, Swapan Senapati
- Computer ScienceOR 2.0/CARE/CLIP/ISIC@MICCAI
- 16 September 2018
The Earth Mover’s Distance based loss function is proposed for training CNN since it takes into account the corresponding ordinal class relationships and shows that the proposed ordinal classification technique outperforms the traditional approaches.
Association of IL12B risk haplotype and lack of interaction with HLA-Cw6 among the psoriasis patients in India
- Aditi Chandra, Swapan Senapati, Saurabh Ghosh, G. Chatterjee, R. Chatterjee
- BiologyJournal of Human Genetics
- 1 March 2017
The data suggested the association of IL 12B with the psoriasis, however no evidence was observed for the epistatic effect of IL12B with HLA-Cw6 among the psOriasis patients in India.