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We recently reported the induction of potent, cross-clade neutralizing antibodies (nAbs) against Human Immunodeficiency Virus type-1 (HIV-1) in rabbits using gp120 based on an M-group consensus sequence. To better characterize these antibodies, 93 hybridomas were generated, which represent the largest panel of monoclonal antibodies (mAbs) ever generated(More)
We recently reported induction of broadly neutralizing antibodies (bnAbs) against multiple HIV-1 (human immunodeficiency virus type 1) isolates in rabbits, albeit weak against tier 2 viruses, using a monomeric gp120 derived from an M group consensus sequence (MCON6). To better understand the nature of the neutralizing activity, detailed characterization of(More)
The success of Bt transgenics in controlling predation of crops has been tempered by sporadic emergence of resistance in targeted insect larvae. Such emerging threats have prompted the search for novel insecticidal molecules that are specific and could be expressed through plants. We have resorted to small RNA-based technology for an investigative search(More)
BACKGROUND AND OBJECTIVES Sexual dimorphism is one of important tool of forensic science. The objective of this study is to assess the dimorphic status of mesio-distal (MD) and bucco-lingual (BL) diameter of mandibular canine with mandibular first molar among the students of dental college. This study is of definite significance as sex chromosomes and(More)
In the last few years, Wireless sensor networks have gained worldwide attention from both the research communities and the actual users. It comprises of a large number of extremely small autonomous computing, communication, and sensing devices, with limited energy and computing capabilities which cooperates to accomplish a large sensing task. Wireless(More)
Orthogonal frequency division multiplexing (OFDM) is a multicarrier modulation technique in which the available spectrum band is divided into number of carriers and all of them are orthogonally modulated. It faces three main challenges i) high PAPR and ii) symbol timing offset iii) carrier frequency offset. In this paper we present a novel timing offset(More)
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