Adelson Francisco Ferreira

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Amphotericin B is one of the most effective antifungal agents; however, its use is often limited owing to adverse effects, especially nephrotoxicity. The purpose of this study was to evaluate the effect of inhibiting the PKA signaling pathway in nephrotoxicity using Amphotericin B from the assessment of cell viability, pro-inflammatory cytokines and nitric(More)
Enhancement of Streptococcus faecalis infection and lowering of the complement level have been demonstrated in mice injected with a heat-treated suspension of baker's yeast (Saccharomyces cerevisiae). The leucocyte response to the infection was not affected. The yeast preparation showed, in vitro, an intense anti-complementary activity on mouse serum and(More)
Amphotericin B is the "gold standard" agent in the management of serious systemic fungal infections. However, this drug can cause nephrotoxicity, which contributes up to 25% of all acute kidney injuries in critically ill patients. Cyclic adenosine monophosphate can protect kidney cells from death due to injury or drug exposure in some cases. Hence, the(More)
Cyclosporine is an important immunosuppressive agent; however, nephrotoxicity is one of the main adverse effects. The purpose of this study was to evaluate the effect of inhibiting the protein kinase A (PKA) signaling pathway in nephrotoxicity caused by cyclosporine from the assessment of cell viability, pro-inflammatory cytokines, and nitric oxide (NO)(More)
Tayza Costa da Silva1, Shirley Antas de Lima2, Josefa Danielma Lopes Ferreira3, Carla Lidiane Jácome de Lima3, Thalys Maynnard Costa Ferreira4, Adriano da Silva Barbosa1, Aline Monteiro Ribeiro Brito1, Thays Leandro dos Santos1, Flávio William Brito de Azevedo Ramalho5, Bianca Fonsêca Anízio2, Adelson Francisco Ferreira2, Marta Miriam Lopes Costa6 1 Nurse,(More)
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