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Magnetic resonance imaging (MRI) is frequently used in the diagnosis of anterior cruciate ligament (ACL) and meniscal injuries. The aim of this retrospective study was to determine the reliability and value of MRI in our management of ACL and meniscal tears. 138 patients who had undergone a MRI to confirm or refute the clinical diagnosis of an ACL or(More)
Heatstroke is often associated with acute kidney injury (AKI). The objectives of this study were to characterize the kidney damage occurring in canine heatstroke using routine and novel biomarkers and to assess their diagnostic and prognostic performance. Thirty dogs with naturally occurring heatstroke were enrolled prospectively. Blood and urine specimens(More)
OBJECTIVE To investigate hemostatic analyte abnormalities and their association with mortality in dogs with naturally occurring heatstroke. DESIGN Prospective observational study. SETTING University teaching hospital. ANIMALS Thirty client-owned dogs with naturally occurring heatstroke. INTERVENTIONS None. MEASUREMENTS AND MAIN RESULTS Citrated(More)
  • Adar Cohen
  • Clinical pharmacology and therapeutics
  • 1976
Sulindac was tested for fecal blood loss in 40 healthy male subjects whose red cells had been labeled with Na2 51 CrO4. Two daily dose levels of 240 mg and 400 mg were compared with 4.8 gm of aspirin and placebo for 2 wk. At day 15, aspirin-induced blood loss was greater than that of both dose levels of sulindac and of placebo (p less than 0.05). There were(More)
Five human volunteers breathed through an inspiratory register to achieve a transdiaphragmatic pressure (Pdi) of 42-45% of the maximum, until fatigue. During the period of resistive breathing all subjects experienced at least one episode of a sudden feeling of relaxation and relief from dyspnea, i.e., "second wind." These episodes were accompanied by a(More)
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