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The use of conventional chemical insecticides and bacterial toxins to control lepidopteran pests of global agriculture has imposed significant selection pressure leading to the rapid evolution of insecticide resistance. Transgenic crops (e.g., cotton) expressing the Bt Cry toxins are now used world wide to control these pests, including the highly(More)
This paper presents the design, implementation and evaluation of a distributed network of smart cameras whose function is to detect and localize falls, an important application in elderly living environments. A network of overlapping smart cameras uses a decentralized procedure for computing inter-image homographies that allows the location of a fall to be(More)
We describe a methodology for creating new technologies for assisted living in residential environments. The number of eldercare clients is expected to grow dramatically over the next decade as the baby boom generation approaches 65 years of age. The UMass/Smith ASSIST framework aims to alleviate the strain on centralized medical providers and community(More)
Normal organogenesis requires co-ordinate development and interaction of multiple cell types, and is seemingly governed by tissue specific factors. Lymphoid organogenesis during embryonic life is dependent on molecules the temporal expression of which is tightly regulated. During this process, haematopoietic 'inducer' cells interact with stromal 'organizer'(More)
NLRs (nucleotide-binding domain leucine-rich-repeat-containing receptors; NOD-like receptors) are a class of pattern recognition receptor (PRR) that respond to host perturbation from either infectious agents or cellular stress. The function of most NLR family members has not been characterized and their role in instructing adaptive immune responses remains(More)
This paper describes the design and preliminary implementation of two distributed smart camera applications: a fall detector and an object finder. These functions are part of a novel suite of applications being developed to address " aging in place " health care technologies. Our approach to these applications is unique in that they are based heavily on(More)
The spatial organization of the genome is thought to play an important part in the coordination of gene regulation. New techniques have been used to identify specific long-range interactions between distal DNA sequences, revealing an ever-increasing complexity to nuclear organization. CCCTC-binding factor (CTCF) is a versatile zinc finger protein with(More)
BACKGROUND With emphasis on the meaningful use of electronic health records, patient portals are likely to become increasingly important. Little is known about patient enrollment in, and use of, patient portals after explicit invitation from providers. OBJECTIVES To examine enrollment in, and use of, an electronic patient portal by race/ethnicity, gender(More)
Sequences proximal to transgene integration sites are able to deregulate transgene expression resulting in complex position effect phenotypes. In addition, transgenes integrated as repeated arrays are susceptible to repeat-induced gene silencing. Using a Cre recombinase-based system we have addressed the influence of transgene copy number (CN) on expression(More)