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Malaria parasites of the genus Plasmodium possess large hyper-variable families of antigen-encoding genes. These are often variantly-expressed and are major virulence factors for immune evasion and the maintenance of chronic infections. Recombination and diversification of these gene families occurs readily, and may be promoted by G-quadruplex (G4) DNA(More)
The evolution of naturalistic, embodied agents and behaviours has been a long-standing goal of Artificial Life since the initial, impressive work of Karl Sims. Incremental evolution has been used extensively to improve the quality of evolutionary search in many complex, non-linear problem spaces. This work sets out to disambiguate the lexicon around(More)
We describe the content and outcomes of the First Workshop on Open-Ended Evolution: Recent Progress and Future Milestones (OEE1), held during the ECAL 2015 conference at the University of York, UK, in July 2015. We briefly summarize the content of the workshop's talks, and identify the main themes that emerged from the open discussions. Two important(More)
2 Today's manufacturing facilities are striving to produce a better product, in a shorter amount of time, and at a lower cost, both for the benefits of the manufacturer and the consumer. To achieve these results, companies have turned to a process methodology called lean that eliminates waste within a production system. Lean manufacturing has brought(More)
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