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- Michael K. Badman, Pavlos Pissios, Adam Richard Kennedy, George Koukos, Jeffrey S. Flier, Eleftheria Maratos-Flier
- Cell metabolism
- 2007
Mice fed a high-fat, low-carbohydrate ketogenic diet (KD) exhibit marked changes in hepatic metabolism and energy homeostasis. Here, we identify liver-derived fibroblast growth factor 21 (FGF21) as… (More)
- Alison M. Wren, Caroline J. Small, +8 authors Stephen R. Bloom
- Endocrinology
- 2000
Ghrelin, a novel 28 amino acid peptide found in hypothalamus and stomach, was recently identified as the endogenous ligand for the growth hormone secretagogue receptor (GHS-R). We have now found that… (More)
- Adam Richard Kennedy, Pavlos Pissios, +9 authors Eleftheria Maratos-Flier
- American journal of physiology. Endocrinology and…
- 2007
Ketogenic diets have been used as an approach to weight loss on the basis of the theoretical advantage of a low-carbohydrate, high-fat diet. To evaluate the physiological and metabolic effects of… (More)
- Caroline R Abbott, Caroline J. Small, +4 authors Stephen R. Bloom
- Brain research
- 2005
The gastrointestinal-derived hormone peptide YY (PYY) is released from intestinal L-cells post-prandially in proportion to calorie intake, and modulates food intake. Peripheral administration of… (More)
- Caroline R Abbott, Michela Rossi, +9 authors Stephen R. Bloom
- Endocrinology
- 2001
Cocaine- and amphetamine-regulated transcript is expressed in hypothalamic regions involved in the central control of food intake. Previous data have implicated cocaine- and amphetamine-regulated… (More)
- Alison M. Wren, Caroline J. Small, +7 authors Stephen R. Bloom
- Endocrinology
- 2002
The central nervous system and gut peptide neuromedin U (NMU) inhibits feeding after intracerebroventricular injection. This study explored the hypothalamic actions of NMU on feeding and the… (More)
- Caroline R Abbott, Adam Richard Kennedy, +7 authors Stephen R. Bloom
- Endocrinology
- 2003
The hypothalamic neuropeptide melanin-concentrating hormone (MCH) increases feeding when injected intracerebroventricularly in rats. To identify the hypothalamic nuclei responsible for the orexigenic… (More)
- Michael K. Badman, Adam Richard Kennedy, Andrew Charles Adams, Pavlos Pissios, Eleftheria Maratos-Flier
- American journal of physiology. Endocrinology and…
- 2009
In mice of normal weight and with diet-induced obesity, a high-fat, low-carbohydrate ketogenic diet (KD) causes weight loss, reduced circulating glucose and lipids, and dramatic changes in hepatic… (More)
- Sabina H Russell, Caroline J. Small, +6 authors Stephen R. Bloom
- Endocrinology
- 2001
The distribution of orexin A-immunoreactive neurons and orexin type I receptors in the CNS suggests important roles in regulating the hypothalamo-pituitary gonadal (HPG) axis and sexual behaviors. We… (More)
- Caroline J. Small, M. L. Goubillon, +9 authors Catherine and Wilson
- Endocrinology
- 2003
Orexin A stimulates GnRH release from hypothalamic explants in vitro. The sites of action of orexin A in the regulation of LH release have been investigated in vivo in ovariectomized rats that were… (More)