Adam R. Bryant

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Acute myeloid leukaemia (AML) is characterised by the halt in maturation of myeloid progenitor cells, combined with uncontrolled proliferation and abnormal survival, leading to the accumulation of immature blasts. In many subtypes of AML the underlying causative genetic insults are not fully described. MicroRNAs are known to be dysregulated during(More)
Acute myeloid leukaemia (AML) with nucleophosmin-1 (NPM1) mutation is a major subtype of AML. The NPM1 mutation induces a myeloproliferative disorder, but evidence indicates that other insults are necessary for the development of AML. We utilised microRNA microarrays and functional assays to determine if microRNA dysregulation could be involved in the(More)
Software reverse engineering involves analyzing computer program executables to understand their structure, functionality, and behavior. In this paper, common reverse engineering functions are decomposed to isolate the information-processing and sensemaking subtasks involved. This paper reviews the applicable literature on eliciting mental models of(More)
A process of sensemaking in reverse engineering was elicited from verbal protocols of reverse engineers as they investigated the assembly code of executable programs. Four participants were observed during task performance and verbal protocols were collected and analyzed from two of the participants to determine their problem-solving states and characterize(More)
—Reverse Code Engineering (RCE) to detect anti-debugging techniques in software is a very difficult task. Code obfuscation is an anti-debugging technique makes detection even more challenging. The Rule Engine Detection by Intermediate Representation (REDIR) system for automated static detection of obfuscated anti-debugging techniques is a prototype designed(More)
BACKGROUND Diagnostic accuracy of lymphoma, a heterogeneous cancer, is essential for patient management. Several ancillary tests including immunophenotyping, and sometimes cytogenetics and PCR are required to aid histological diagnosis. In this proof of principle study, gene expression microarray was evaluated as a single platform test in the differential(More)
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