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- Publications
- Influence
trans-2-(2,5-Dimethoxy-4-iodophenyl)cyclopropylamine and trans-2-(2,5-dimethoxy-4-bromophenyl)cyclopropylamine as potent agonists for the 5-HT2 receptor family
- Adam Pigott, S. Frescas, J. McCorvy, X. Huang, B. Roth, D. Nichols
- Medicine, Chemistry
- Beilstein journal of organic chemistry
- 8 October 2012
A strategy to replace the ethylamine side chain of 2,5-dimethoxy-4-iodoamphetamine (DOI, 1a), and 2,5-dimethoxy-4-bromoamphetamine (DOB, 1b) with a cyclopropylamine moiety was successful in leading… Expand
Total synthesis of ( /-)-nicolaioidesin B via a highly regio- and diastereoselective Diels-Alder reaction
- Adam Pigott, R. Lepage, J. White, M. J. Coster
- Chemistry
- 10 December 2014
The total synthesis of (+/-)-nicolaioidesin B, a natural product that shows preferential cytotoxicity against pancreatic cancer cells under nutrient starvation conditions, is achieved. The key step… Expand