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What determines the decision of an inventor to seek patent protection in a foreign jurisdiction, particularly one where intellectual property rights protection is weak? This paper focuses on competition as a determinant of the patenting decision in the context of the recent foreign patenting surge in China. Using a database that comprises of all patents(More)
BACKGROUND We and others have previously reported significant changes in chloride transport after cationic-lipid-mediated transfer of the cystic fibrosis transmembrane conductance regulator (CFTR) gene to the nasal epithelium of patients with cystic fibrosis. We studied the safety and efficacy of this gene transfer to the lungs and nose of patients with(More)
The success of Japanese manufacturing firms such as Honda and Toyota has renewed attention to the importance of cost reduction on existing products as a source of productivity growth. Using survey data and interviews, this paper explores the determinants of average-cost reduction for a sample of 207 automotive suppliers in the United States and Canada(More)
Ruberman, to my fellow students, and to the kind and supportive staff of the Brandeis Mathematics Department. I would like to thank all my family and friends for their love and encouragement with patience and I wish to express my boundless love to my wife, Arifun Chowdhury. This thesis is dedicated to my parents, Md. Enamul Huq and Mahbub Ara Ummeh Sultana,(More)
Infection with respiratory syncytial virus (RSV) is one of the major causes globally of childhood respiratory morbidity and hospitalization. Palivizumab, a humanized monoclonal antibody, has been recommended for high risk infants to prevent severe RSV-associated respiratory illness. This recommendation is based on evidence of efficacy when used under(More)
We estimate an econometric model of the propensity of firms to engage in research joint ventures (RJVs), in order to explain the recent precipitous decline in RJVs filed with the U.S. Department of Justice. We find that RJV activity is inversely related to the competitive position of U.S. firms in global high-technology industries and that the establishment(More)
There is evidence of intestinal inflammation in patients with CF. Intestinal inflammation may negatively impact the nutritional status of patient with CF, which adversely affects pulmonary function and survival. This paper provides an up-to-date review of intestinal inflammation in CF and an evaluation of utility of two specific faecal inflammatory markers(More)
Since the mid-1980s many authors have investigated the influence of information technology (IT) on productivity. Until recently there has been no clear evidence that productivity increases as a result of IT spending. This productivity paradox is partly due to the difficulty in correctly identifying outputs, particularly in the service sector such as the(More)