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Correlation between an In Vitro Invasion Assay and a Murine Model of Burkholderia cepacia Lung Infection
ABSTRACT Our understanding of the virulence of Burkholderia cepacia complex lung infections in cystic fibrosis patients is incomplete. There is a great deal of variability in the clinical course,Expand
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Invasion of respiratory epithelial cells by Burkholderia (Pseudomonas) cepacia.
Pulmonary infections caused by Burkholderia (Pseudomonas) cepacia are an important cause of morbidity and mortality in cystic fibrosis (CF) patients. Several features suggestive of cellular invasionExpand
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Contribution of Burkholderia cenocepacia Flagella to Infectivity and Inflammation
ABSTRACT Burkholderia cenocepacia is an opportunistic pathogen that can cause severe lung infections in cystic fibrosis patients. To understand the contribution of B. cenocepacia flagella toExpand
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Salicylate induces an antibiotic efflux pump in Burkholderia cepacia complex genomovar III (B. cenocepacia).
An antibiotic efflux gene cluster that confers resistance to chloramphenicol, trimethoprim, and ciprofloxacin has been identified in Burkholderia cenocepacia (genomovar III), an important cysticExpand
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Attenuated Virulence of a Burkholderia cepacia Type III Secretion Mutant in a Murine Model of Infection
ABSTRACT Type III secretion systems are utilized by a number of gram-negative bacterial pathogens to deliver virulence-associated proteins into host cells. Using a PCR-based approach, we identifiedExpand
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Functional selectivity of dopamine D1 receptor agonists in regulating the fate of internalized receptors
Recently, we demonstrated that D(1) agonists can cause functionally selective effects when the endpoints of receptor internalization and adenylate cyclase activation are compared. The present studyExpand
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Transcytosis of Gastrointestinal Epithelial Cells by Escherichia coli K1
Escherichia coli K1 is an important neonatal pathogen that is usually transferred from maternal to infant gastrointestinal tract at the time of parturition. Approximately 20% of neonates areExpand
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Optimized In Vitro Antibiotic Susceptibility Testing Method for Small-Colony Variant Staphylococcus aureus
ABSTRACT Staphylococcus aureus small-colony variants (SCVs) emerge frequently during chronic infections and are often associated with worse disease outcomes. There are no standardized methods for SCVExpand
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Nutrient and Physical Soil Characteristics of River Cane Stands, Western North Carolina
Abstract Arundinaria gigantea (Walt.) Muhl., commonly called river cane, is a member of the grass family (Poaceae). The primary purpose of this research is to characterize the physical and chemicalExpand
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