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Necessary and sufficient conditions are obtained for the Lipschitzian stability of local solutions to finite-dimensional parameterized optimization problems in a very general setting. Properties of prox-regularity of the essential objective function and positive defi-niteness of its coderivative Hessian are the key to these results. A previous… (More)
Four cases are reported in which substantial depression was associated with the use of the calcium channel blocker nifedipine. In one instance, a patient became unresponsive to treatment with nortriptyline when nifedipine was introduced. In each case, the depression resolved following discontinuation of nifedipine. Possible mechanisms by which nifedipine… (More)
Subgradient mappings have many roles in variational analysis, such as the formulation of optimality conditions and, in the special case of normal cone mappings, the statement and analysis of variational inequalities and related expressions. Central to the study of perturbations of solutions to systems of conditions in which subgradient mappings appear are… (More)
The ventricular-brain ratios (VBRs) of 32 chronic schizophrenic men were determined by CAT scan. Ten of the 12 patients with VBRs above 8.4% had made suicide attempts, compared with two of the 20 patients with VBRs below 8.4%.
The neuroendocrinology of bulimia nervosa has only recently been investigated, with initial research suggesting some biological overlap with both anorexia nervosa (AN) and depression. Similarities among AN, depression, and bulimia include a nonsuppressed Dexamethasone Suppression Test and an abnormal growth hormone (GH) response to thyrotropin-releasing… (More)
A case is reported of delirium and seizures due to the abrupt withdrawal from the benzodiazepine alprazolam. Because of their short half-life, agents such as alprazolam may present a greater risk of withdrawal reactions than longer acting agents.