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Parkinson disease (PD) is a neurodegenerative disorder afflicting more than 1 million aging Americans, incurring $23 billion in annual medical costs in the U.S. alone. Approximately 90% Parkinson patients undergoing treatment have mobility related problems related to medication which prevent them doing their activities of daily living. Efficient management(More)
In the past, the music community conducted research on what makes music more musical or expressive. Much of this work has focused on the manipulation of phrasing, articulation and rubato to make music more expressive. However, it has been difficult to study neuromuscular control used by experts to create such musical music. This paper took a first step(More)
Recent studies using simple model systems have demonstrated that continuous countercurrent tangential chromatography (CCTC) has the potential to overcome many of the limitations of conventional Protein A chromatography using packed columns. The objective of this work was to optimize and implement a CCTC system for monoclonal antibody purification from(More)
This paper describes an algorithm for generating a planar image that when tilted provides stereo cues to slant, without contamination from pictorial gradients. As the stimuli derived from this image are ultimately intended for use in studies of slant perception under magnification, a further requirement is that the generated image be suitable for(More)
We present a novel and relatively simple method for clustering pixels into homogeneous patches using a directed graph of edges between neighboring pixels. For a 2D image, the mean and variance of image intensity is computed within a circular region centered at each pixel. Each pixel stores its circle’s mean and variance, and forms the node in a graph, with(More)
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