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Treatment of chronic hepatitis C in human immunodeficiency virus (HIV)-infected patients is associated with low response rates and high incidence of side effects. One hundred twenty-one hepatitis C virus (HCV)-HIV-coinfected patients were randomized to receive interferon alpha-2b (3 MU thrice weekly; n = 61) or peginterferon alpha-2b (1.5 microg/kg/week; n… (More)
Varicella-zoster virus (VZV) pneumonia is one of the most serious complications of this infection in adults. The objective of this study was to analyze the epidemiological and clinical characteristics in a large sample of patients with VZV pneumonia. This was a 10-y retrospective, descriptive, observational study. We studied 46 patients with VZV pneumonia,… (More)
BACKGROUND We hypothesized that obstructive sleep apnea (OSA) can predispose individuals to lower airway infections and community-acquired pneumonia (CAP) due to upper airway microaspiration. This study evaluated the association between OSA and CAP. METHODS We performed a case-control study that included 82 patients with CAP and 41 patients with other… (More)
OBJECTIVE Our aim was to compare clinical and polysomnographic variables in pediatric patients with sleep apnea-hypopnea syndrome (SAHS) secondary to tonsillar hypertrophy with those in patients with concomitant disease. PATIENTS AND METHODS We studied 42 children with SAHS (mean [SD] age, 8  years; body mass index [BMI], 19.6 [5.2] kg/m2; neck… (More)
This study was aimed to evaluate the efficacy of a home based program on clinical response, CPAP compliance and cost in a population of high pre-test probability of suffering obstructive sleep apnea syndrome (OSAS). Patients were randomized into three groups: A: home respiratory polygraphy (RP) and home follow-up; B: hospital polysomnography and hospital… (More)
We report the case of a patient with chronic renal failure and primary hyperparathyroidism who developed nonhypercapnic central sleep apnea syndrome (CSAS), which was multifactorial in origin and attributed to metabolic factors. Given an inadequate response to oxygen therapy and continuous positive airway pressure (CPAP) revealed by several polygraph… (More)
Three cases of pleural empyema caused by Gemella species--2 caused by Gemella morbillorum and 1 caused by G haemolysansare reported. Microbiological characteristics, predisposing factors, and treatment are reviewed and all cases published in the literature are analyzed.