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The nude mouse has several advantages for the study of human tumours. Compared to adult cancers (Sharkey et al., 1978), paediatric tumours have been less extensively xenografted into nude mice (Helson, 1982). The only large series was published by Neely et al. (1983). Most infantile solid tumours are considered embryonic because of the age at which they(More)
Local injection of mouse mammary tumor virus (MMTV) induces a local immune response, with activation of viral superantigen (vSAG)-specific T cell subsets followed by their clonal deletion. We investigated the fate of vSAG-reactive T cells following footpad injection of MMTV(SW) to mice. Activated T cells accumulated in draining lymph nodes. However, we(More)
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