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BACKGROUND Migraine is one of the most frequent disabling neurological conditions with a major impact on the patients' quality of life. OBJECTIVES To give evidence-based or expert recommendations for the different drug treatment procedures in the particular migraine syndromes based on a literature search and the consensus of an expert panel. METHODS All(More)
BACKGROUND Several studies suggest an association between migraine and juvenile stroke. Because of some shortcomings, we designed another case-control study of a homogenous group of patients with juvenile cerebral ischemia. This study is part of a larger German epidemiological research project on the association of migraine with cerebrovascular disease. (More)
Impairment of cognitive skills is found in up to 65% of patients suffering from multiple sclerosis (MS). Little is known concerning the natural history or characteristics of progression of these cognitive dysfunctions. Furthermore, it has not been investigated to date whether there are differences in the course of cognitive impairment with respect to(More)
Migraine is one of the most frequent disabling neurological conditions with a major impact on the patients' quality of life. To give evidence-based or expert recommendations for the different drug treatment procedures of the different migraine syndromes based on a literature search and an consensus in an expert panel. All available medical reference systems(More)
OBJECTIVE S: To provide data on the demography, clinical features, and comorbidity of headache associated with sexual activity (HSA). METHODS Between 1996 and 2001, 51 patients with the diagnosis of HSA were questioned using a structured interview. RESULTS The mean age at onset was 39.2 (+/-11.1) years. There was a clear male preponderance (2.9:1). The(More)
Sirs: In the past, the precipitating factors of transient global amnesia (TGA) have been mostly reported anecdotally (“amnesia at the seaside”). Only in the last 2 decades have systematic studies of these factors been performed. The proportion of patients who reported unusual precipitating activity have ranged between 30 and 69% [2, 3, 9, 11]. We undertook(More)
Patients with HIV infection often complain of cognitive disturbances, which can be related to AIDS dementia or HIV-associated encephalopathy (HIVE). We investigated the impact of highly active antiretroviral therapy (HAART) in comparison with other therapeutic regimens on the progression of these cognitive disturbances as measured by visual event-related(More)
OBJECTIVES Almost 100 years after the first report of the thalamic syndrome, the scientific basis for the treatment of central post-stroke pain (CPSP) is remarkably small. Therefore, the authors aimed to provide evidence-based recommendations for the treatment of CPSP. METHODS The authors performed a systematic review of the literature on the(More)
Botulinum toxin A has been suggested to be effective in the prophylactic treatment of migraine. However, only very few randomized, double-blind, placebo-controlled studies are available. We designed such a study with a specific focus on different injection sites. Sixty patients with a migraine according to the criteria of the International Headache Society(More)
Chronic hypoxaemia in chronic obstructive pulmonary disease is a well known risk factor for polyneuropathy but the impact of intermittent hypoxaemia on peripheral nerve function has not been established so far. A case-control study was performed to evaluate the prevalence of polyneuropathy in obstructive sleep apnoea (OSA). Out of 24 patients with OSA, 17(More)