Achille Marino

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Classification of juvenile idiopathic arthritis is an ongoing process and up to now has been predominantly based on clinical manifestations--mainly number of joints at onset of disease. In the meantime, basic studies have advanced our knowledge regarding the disease pathogenesis. Unfortunately, studies of cytokines and cytokine polymorphisms have not(More)
The seroprevalence to Toxoplasma gondii (41.1%), rubella virus (88.2%), cytomegalovirus (86.0%), and herpes simplex virus (80.0%) has been evaluated in fertile women living in Catania (Sicily). The population group studied was divided into four age groups to quantify the risk of primary infection in each age group.
BACKGROUND Data from routine clinical practice are needed to further define the efficacy and safety of biologic medications in children with juvenile idiopathic arthritis (JIA). The aim of this analysis was to investigate the disease status, reasons for discontinuation and adverse events in Italian JIA patients treated with etanercept (ETN). METHODS In(More)
The seroprevalence of antibodies to measles, mumps, and rubella viruses (MMR) was determined in 1498 subjects in Catania, Italy, ranging in age from 1 month to 25 years. The study population was divided into seven age groups and sceeened by enzyme immunoassay using microquantities (10 μl) of whole blood collected by fingerprick on filterpaper discs. The(More)
Introduction Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood. Localized scleroderma also known as morphea is an inflammatory, fibrosing skin disorder that leads to sclerosis of the dermis and eventually of the underlying tissues. The prevalence is estimated at around 1-9/100,000 with the onset before 10 years of(More)
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children and an important cause of short and long-term disability. JIA encompasses several disease categories, each of which has distinct presentation, clinical manifestations, and, presumably, genetic background and etiopathogenesis. Correct choice and timely use of(More)