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- Ron Kohen, Abraham Nyska
- Toxicologic pathology
- 2002
Reactive oxygen species (ROS) and other radicals are involved in a variety of biological phenomena, such as mutation, carcinogenesis, degenerative and other diseases, inflammation, aging, and… (More)
We present a general methodology for performing statistical inference on the components of a real-valued matrix parameter for which rows and columns are subject to order restrictions. The proposed… (More)
- Bob J J M Thoolen, Robert R. Maronpot, +14 authors Jerrold M Ward
- Toxicologic pathology
- 2010
The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a joint initiative of the Societies of Toxicologic Pathology from Europe… (More)
- Urmila P Kodavanti, Carolyn F. Moyer, +5 authors Abraham Nyska
- Toxicological sciences : an official journal of…
- 2003
Epidemiologists have associated particulate matter (PM) air pollution with cardiovascular morbidity and premature mortality worldwide. However, experimental evidence demonstrating causality and… (More)
- Urmila P Kodavanti, Ronald F. Thomas, +15 authors Narasimham L. Parinandi
- Environmental health perspectives
- 2011
BACKGROUND
Mechanisms of cardiovascular injuries from exposure to gas and particulate air pollutants are unknown.
OBJECTIVE
We sought to determine whether episodic exposure of rats to ozone or… (More)
- James C. Bonner, Annette B. Rice, +8 authors Robert I Langenbach
- The American journal of pathology
- 2002
The cyclooxygenase (COX)-2 enzyme has been implicated as an important mediator of pulmonary fibrosis. In this study, the lung fibrotic responses were investigated in COX-1 or COX-2-deficient (-/-)… (More)
- Nigel J. Walker, Patrick Crockett, +10 authors Christopher J. Portier
- Environmental health perspectives
- 2005
Use of the dioxin toxic equivalency factor (TEF) approach in human risk assessments assumes that the combined effects of dioxin-like compounds in a mixture can be predicted based on a… (More)
- Yael Pewzner-Jung, Ori Brenner, +15 authors Anthony H Futerman
- The Journal of biological chemistry
- 2010
We have generated a mouse that cannot synthesize very long acyl chain (C22-C24) ceramides (Pewzner-Jung, Y., Park, H., Laviad, E. L., Silva, L. C., Lahiri, S., Stiban, J., Erez-Roman, R., Brugger,… (More)
- Andrew W Suttie, Abraham Nyska, Joseph K. Haseman, Glenda J Moser, Theleria R Hackett, Thomas L. Goldsworthy
- Toxicologic pathology
- 2003
To improve the precision and consistency of experimental results, we have developed a scoring system for proliferative epithelial lesions in the mouse prostate based on histological growth patterns… (More)
- P. C. Y. Chan, Joseph K. Haseman, Jesse Prejean, Abraham Nyska
- Toxicology letters
- 2003
These investigations of riddelliine analyzed potential carcinogenesis and the utility of the female-rat/male-mouse design in bioassays and dose-response. Groups of 50 Fischer rats and B6C3F1 mice… (More)