Abraham Goldin

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The antigenicity of several well established Moloney virus-induced transplantable leukemias was studied. Resistance was developed by pretreatment of isologous mice with x-radiated tumor tissue. In general, the neoplasms grew more rapidly in preirradiated mice (400 r) than in normal mice, and at low inoculum concentrations a higher percentage of tumors was(More)
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at(More)
Studies on the effectiveness of drug combina tions have intrigued pharmacologists for decades. Combinations of drugs have been used in attempts to attain enhanced biological effects. The range of pharmacological interests in which drug combina tions have been studied is diverse, including anal gesics, insecticides, fungicides, antibiotics, plant and animal(More)
Short-term exposure of L1210 Ha leukemia to DTIC in vivo or in vitro resulted in the generation of leukemic cells that were moderately immunogenic for histocompatible (BALB/C × DBA/2)F1 (CD2F1) mice. In vivo treatment was carried out in the peritoneal cavity of CD2F1 host for 8–36 h. In vitro experiments were performed in glass vessels, in which tumor cells(More)