Abigail Davies

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Clostridium difficile is a major problem as an aetiological agent for antibiotic-associated diarrhoea. The mechanism by which the bacterium colonizes the gut during infection is poorly understood, but undoubtedly involves a myriad of components present on the bacterial surface. The mechanism of C. difficile surface-layer (S-layer) biogenesis is also largely(More)
– Ontologies have been used for the purpose of bringing system and consistency to subject and knowledge areas. We present a criticism of the present mathematical structure of ontologies and indicate that they are not sufficient in their present form to represent the many different valid expressions of a subject knowledge domain. We propose an alternative(More)
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