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Human red blood cells are lysed by the neutrophil-derived oxidant hypochlorous acid (HOCl), although the mechanism of lysis is unknown. Hypobromous acid (HOBr), a similarly reactive oxidant, lysed red cells approx. 10-fold faster than HOCl. Therefore we compared the effects of these oxidants on thiols, membrane lipids and proteins to determine which(More)
CATRINA A. MACKENZIE 1 ∗,COLIN A. CHAPMAN 2 , 3 AND RAJA SENGUP T A 1 , 2 1Department of Geography, McGill University, 805 Rue Sherbrooke Ouest, Montreal, Quebec H3A 2K6, Canada, 2McGill School of Environment and Department of Anthropology, McGill University, Montreal, Quebec H3A 2T7, Canada and 3Wildlife Conservation Society, Bronx, New York, NY, USA Date(More)
Scanning electron microscopy of the bronchiolar neuroepithelial bodies (NEB's) in the neonatal mouse lungs was undertaken and correlated with the accompanying transmission electron microscopy. The NEB's appeared as isolated organoids along the entire length of the bronchioles, and often were located at the branching points. The boundary of the NEB's was(More)
A laboratory based epidemiologic study was done to determine the possible relationship of herpesvirus type 2 to carcinoma of the prostate. A total of 305 patients (224 with benign prostatic hypertrophy and 81 with prostatic carcinoma) who underwent transurethral resection of the prostate was studied. Viral cultures were obtained from urethral swabs and(More)
A light and electron microscopic study was made of lymphatic tissues from 2 dogs with reticulum cell leukemia. Virus-like particles were found in both dogs. Cultures of leukemic cells were established from both dogs and 1 culture contained numerous C type virus-like particles. Mycoplasma canis was recovered from the pleural fluid and pleural fluid cell(More)
Thirty-four neonatal beagles were inoculated with cells obtained originally from 2 adult beagles, 1 with lymphocytic leukemia, the other with generalized malignant lymphoma. Most of the puppies were irradiated before inoculation; a few were inoculated in utero and were not irradiated. Of the 11 puppies inoculated with buffy coat cells of the blood from the(More)