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Modern parallel computing hardware demands increasingly specialized attention to the details of scheduling and load balancing across heterogeneous execution resources that may include GPU and cloud environments, in addition to traditional CPUs. Many existing solutions address the challenges of particular resources, but do so in isolation, and in general do(More)
Achieving the performance potential of an Exascale machine depends on realizing both operational efficiency and scalability in high performance computing applications. This requirement has motivated the emergence of several new programming models which emphasize fine and medium grain task parallelism in order to address the aggravating effects of asynchrony(More)
Most of HPC services are still designed around a centralized paradigm and hence are susceptible to scaling issues. P2P services have proved themselves at scale for wide-area internet workloads. Distributed key-value stores (KVS) are widely used as a building block for these services, but are not prevalent in HPC services. In this paper, we simulate KVS for(More)
Owing to the significant high rate of component failures at extreme scales, system services will need to be failure-resistant, adaptive and self-healing. A majority of HPC services are still designed around a centralized paradigm and hence are susceptible to scaling issues. Peer-to-peer services have proved themselves at scale for wide-area internet(More)
Owing to the extreme parallelism and the high component failure rates of tomorrow's exascale, high-performance computing (HPC) system software will need to be scalable, failure-resistant, and adaptive for sustained system operation and full system utilizations. Many of the existing HPC system software are still designed around a centralized server paradigm(More)
OSCAR has matured over the years into a very capable, yet simple high-performance clustering platform solution. Ease of building and administrating a cluster, effective resource management and scalable performance are some of the issues which have gathered a lot of focus in the HPC domain lately. This technical paper describes the integration of OSCAR and(More)
The precise recognition of appropriate synaptic partner neurons is a critical step during neural circuit assembly. However, little is known about the developmental context in which recognition specificity is important to establish synaptic contacts. We show that in the Drosophila visual system, sequential segregation of photoreceptor afferents, reflecting(More)
Long-running HPC applications guard against node failures by writing checkpoints to parallel file systems. Writing these checkpoints with petascale class machines has proven difficult and the increased concurrency demands of exascale computing will exacerbate this problem. To meet checkpointing demands and sustain application-perceived throughput at(More)
Domain-specific languages offer programming abstractions that enable higher efficiency, productivity and portability specific to a given application domain. Domain-specific languages such as StreamIt have valuable auto-parallelizing code-generators, but they require learning a new language and tool-chain and may not integrate easily with a larger(More)
The execution of a SPMD application involves running multiple instances of a process with possibly varying arguments. With the widespread adoption of massively multicore processors, there has been a focus towards harnessing the abundant compute resources effectively in a power-efficient manner. Although much work has been done towards optimizing distributed(More)