Abhilash Thakur

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Benzodiazepine is an antixylotic agent , induce and maintain sleep, reduce seizures, and induce conscious sedation. It acts as a positive allosteric modulator of GABAA receptor. The binding of benzodiazepine analogues to this allosteric modulatory site enhances the affinity of GABA (Gama amino butyric acid) for the agonist recognition site. In the present(More)
This work describes QSAR and SAR studies on the reduction of 27 aromatic nitro compounds by xanthine oxidase using both distance-based topological indices and quantum molecular descriptors along with indicator parameters. The application of a multiple linear regression analysis indicated that a combination of distance-based topological indices with the ad(More)
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