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The antiviral thymidine analog azidothymidine (AZT) is used to treat several virus-associated human cancers. However, to date the mechanism of AZT action remains unclear and thus, reasons for treatment failure are unknown. Adult T-cell leukemia/lymphoma (ATL) is an aggressive malignancy of poor prognosis. Here, we report that enduring AZT treatment of(More)
In this paper, a fully automatic method for gridding bright field images of bead-based microarrays is proposed. There have been numerous techniques developed for gridding fluorescence images of traditional spotted microarrays but to our best knowledge, no algorithm has yet been developed for gridding bright field images of bead-based microarrays. The(More)
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