Abhijit Saha

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Indolicidin (IR13), a 13-residue antimicrobial peptide from the cathelicidin family, is known to exhibit a broad spectrum of antimicrobial activity against various microorganisms. This peptide inhibits bacterial DNA synthesis resulting in cell filamentation. However, the precise mechanism remains unclear and requires further investigation. The central PWWP(More)
National Optical Astronomy Observatory, 950 N. Cherry Ave, Tucson, AZ 85719 Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550 Physics Department, University of California, One Shields Avenue, Davis, CA 95616 Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 U.S. Naval Observatory Flagstaff Station,(More)
Herein, we report a novel hexapeptide, derived from activity dependent neuroprotective protein (ADNP), that spontaneously self-assembles to form antiparallel β-sheet structure and produces nanovesicles under physiological conditions. This peptide not only strongly binds with β-tubulin in the taxol binding site but also binds with the microtubule lattice in(More)
Microtubule dynamics play a crucial role in cancer cell division. Various drugs are developed to target microtubule. Although a few of them show potential in treatment of cancer, but success rate is limited due to their poor bioavailability and lack of specificity. Thus, development of highly bioavailable and target specific anticancer drug is extremely(More)
Selective quenching of luminescence of quantum dots (QDs) by Cu2+ ions vis-à-vis other physiologically relevant cations has been reexamined. In view of the contradiction regarding the mechanism, we have attempted to show why Cu2+ ions quench QD-luminescence by taking CdS and CdTe QDs with varying surface groups. A detailed study of the solvent effect and(More)
Electrospun membranes of polycaprolactone are widely used for biomedical applications like wound dressings and tissue engineering scaffolds. It is important to sterilize this material using the most accepted method, the gamma irradiation. In this study, we have evaluated the sterilizability of electrospun polycaprolactone membranes with gamma radiation of(More)