Abhijeet Anand

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1. The sensations evoked by the injection of lobeline into the right antecubital vein were studied in 8 subjects after bilateral lung transplantation and 10 control subjects. In control subjects, two distinct sensations were experienced. There was an early noxious sensation (onset approximately 10 s) followed by a late sensation of breathlessness (onset(More)
1. Experiments carried out on anaesthetized cats showed that increasing blood flow, through the lobes of a lung, by 133% (S.E. 33%) generated an average of 0.75 impulses/sec (S.E. 0.3) in ten almost silent J receptors. Equivalent activity was produced by injecting 12-18 micrograms phenyl diguanide/kg into the right atrium. Such activity caused marked reflex(More)
OBJECTIVE The objective of this study was to evaluate the applicability of the discrimination parameters Mahalanobis distance, spectral residuals, and limit tests, developed by this group to differentiate normal from malignant colon tissues. BACKGROUND DATA Colon cancers are diagnosed using fiberoptic endoscopic localization and a subsequent(More)
In whatever mammalian receptor system Merkel cells are found, they are always associated with a characteristic slowly adapting response. The role of Merkel cells in the transduction process of slowly adapting Type I cutaneous mechanoreceptors (SAI receptors or touch domes) of rats and cats was investigated by mechanical and electrical stimulation of SAI(More)
1. Intravenous injections of lobeline HCl into twenty-six normal young male human volunteers produced sensations of choking, pressure or fumes in the throat and upper chest at a mean threshold dose of 12 micrograms kg-1. 2. Reflex changes in breathing pattern usually appeared just before the sensations. Increasing the dose of lobeline increased the(More)
1. The responses of J receptors to certain excitants were recorded during pulmonary oedema produced by phosgene gas (320-1080 p.p.m.) or alloxan, 150 mg kg-1 i.v., in cats anaesthetized with sodium pentobarbitone, 35 mg kg-1 I.P. 2. The responses of fourteen (out of fifteen) J receptors to phenyl diguanide (PDG) were greatly enhanced after phosgene, the(More)
C amillo Golgi and Ramon Y Cajal shared the Nobel Prize in Physiology and Medicine in 1906 for their studies on the structure of nervous system. Strangely they met only at Stockholm. Golgi gave his Nobel lecture first in which he described his reticular theory of neuronal network. This was contradicted by Cajal in his Nobel lecture, who advocated the(More)