Abderrahim Lomri

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Reactive oxygen species and superoxide dismutases: role in joint diseases.

Valéry Afonso, Romuald Champy, Dragoslav R Mitrovic, Pascal Collin, Abderrahim Lomri
Joint, bone, spine : revue du rhumatisme
2007

Reactive oxygen species (ROS) are produced in many normal and abnormal processes in humans, including atheroma, asthma, joint diseases, aging, and cancer. The superoxide anion O(2)(-) is the main… (More)

Bone morphogenetic protein-2 and transforming growth factor-beta2 interact to modulate human bone marrow stromal cell proliferation and differentiation.

Olivia Fromigué, Pierre Jacques Marie, Abderrahim Lomri
Journal of cellular biochemistry
1998

Osteoprogenitor cells in the human bone marrow stroma can be induced to differentiate into osteoblasts under stimulation with hormonal and local factors. We previously showed that human bone marrow… (More)

Increased proliferation of osteoblastic cells expressing the activating Gs alpha mutation in monostotic and polyostotic fibrous dysplasia.

Pierre Jacques Marie, C de Pollak, Philippe Chanson, Abderrahim Lomri
The American journal of pathology
1997

We studied the osteoblastic abnormalities resulting from activating mutation of the Gs alpha gene in two patients with McCune-Albright syndrome and one patient with monostotic fibrous dysplasia.… (More)

Culture and behavior of osteoblastic cells isolated from normal trabecular bone surfaces

Pierre Jacques Marie, Abderrahim Lomri, Ayman Sabbagh, Michel Félix Baslé
In Vitro Cellular & Developmental Biology
1989

We report the characterization of human osteoblastic cells that were derived from the surface of trabecular bone fragments. After removal of bone marrow cells, the bone lining osteoblastic cells… (More)

Syndecan-2 is involved in the mitogenic activity and signaling of granulocyte-macrophage colony-stimulating factor in osteoblasts.

Dominique Modrowski, Mheboob Aalam V Basle, Abderrahim Lomri, Pierre Jacques Marie
The Journal of biological chemistry
2000

We previously showed that granulocyte-macrophage colony-stimulating factor (GM-CSF) binds to heparan sulfate proteoglycans expressed at the surface of osteoblastic cells and that the mitogenic… (More)

Increased expression of protein kinase Calpha, interleukin-1alpha, and RhoA guanosine 5'-triphosphatase in osteoblasts expressing the Ser252Trp fibroblast growth factor 2 receptor Apert mutation:…

Abderrahim Lomri, Jérôme Lemonnier, Philippe Delannoy, Pierre Jacques Marie
Journal of bone and mineral research : the…
2001

Apert (Ap) syndrome is a craniofacial malformation characterized by premature fusion of cranial sutures (craniosynostosis). We previously showed that the Ser252Trp fibroblast growth factor receptor 2… (More)

Osteocalcin and deoxyribonucleic acid synthesis in vitro and histomorphometric indices of bone formation in postmenopausal osteoporosis.

Pierre Jacques Marie, Abdulrahman Jafar Sabbagh, M C De vernejoul, Abderrahim Lomri
The Journal of clinical endocrinology and…
1989

The aim of this study was to determine whether abnormal osteoblastic growth and/or differentiation play a role in the decreased bone formation in women with postmenopausal osteoporosis. To do so, we… (More)

Negative regulation of superoxide dismutase-1 promoter by thyroid hormone.

Guilherme M Santos, Valéry Afonso, +5 authors Abderrahim Lomri
Molecular pharmacology
2006

The role of thyroid hormone [L-3,5,3'-triiodothyronine (T3)] and the thyroid hormone receptor (TR) in regulating growth, development, and metabolic homeostasis is well established. It is also… (More)

Tumor necrosis factor-alpha down-regulates human Cu/Zn superoxide dismutase 1 promoter via JNK/AP-1 signaling pathway.

Valéry Afonso, Guilherme M Santos, +5 authors Abderrahim Lomri
Free radical biology & medicine
2006

Overexpression of Cu/Zn superoxide dismutase 1 (SOD1) in monocytes blocks reactive oxygen species-induced inhibition of cell growth and apoptosis and renders cells resistant to the toxic effect of… (More)

Skeletal unloading induces biphasic changes in insulin-like growth factor-I mRNA levels and osteoblast activity.

Hicham Drissi, Abderrahim Lomri, Françoise Lasmoles, Xavier Holy, Eric Zerath, Pierre Jacques Marie
Experimental cell research
1999

To determine the local mechanisms involved in the effects of skeletal unloading on bone formation, we studied the temporal pattern of mRNA levels for insulin-like growth factor-I (IGF-I), IGF-I… (More)

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