Abdel Maksoud

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Immunotherapy strategies aimed at increasing human Valpha24(+)Vbeta11(+) natural killer T (NKT) cell numbers are currently a major focus. To provide further information towards the goal of NKT cell-based immunotherapy, we assessed the effects of age, cancer status and prior anticancer treatment on NKT cell numbers and their expansion capacity following(More)
Psoriasis, a common skin disease in Egypt, has drawn much attention to study the potential role of immunity in its pathogenesis.. Exposure of skin to microbial antigens and other stressful stimuli can induce heat shock proteins (HSPs) expression. HSPs comprise a large number of antigens against which immune responses are directed, owing to their(More)
Psoriasis, a common skin disease in Egypt, has drawn much attention to study the potential role of immunity in its pathogenesis.. Exposure of skin to microbial antigens and other stressful stimuli can induce heat shock proteins (HSPs) expression. HSPs comprise a large number of antigens against which immune responses are directed, owing to their(More)
The objective of this study was to assess serum CXCL5 and PDCD-4 levels in patients with colorectal cancer (CRC) to evaluate their value as prognostic markers and their correlation with clinicopathologic features. The study was conducted on 103 colorectal cancer patients divided into two groups according to stage of disease (early [groupI] and late [group(More)
BACKGROUND Many clinical trials of DC-based immunotherapy involve administration of monocyte-derived DCs (Mo-DC) on multiple occasion. We aimed to determine tbe optimal cell processing procedures and timing (leukapheresis, RBC depletion and cryopreservation) for generation of Mo-DC for clinical purposes. METHODS Leukapheresis was undertaken using a COBE(More)
Immunotherapy strategies aimed at increasing human Vα24+Vβ11+ natural killer T (NKT) cell numbers are currently a major focus. To provide further information towards the goal of NKT cell-based immunotherapy, we assessed the effects of age, cancer status and prior anticancer treatment on NKT cell numbers and their expansion capacity following(More)
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