Abazar Roustazadeh

1Amaneh Yarnazari
1Bahram Kazemi
1Abdollah Amirfarhangi
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BACKGROUND We studied the association between erythrocyte glutathione peroxidase1 (GPx1) activity and rs1050450 (Pro198Leu) site with the stenosis of coronary arteries and, evaluated the Pro/Leu position within the predicted tertiary structure. METHODS Subjects were recruited from who underwent coronary angiography (controls; n = 55, Stenosis < 5% and(More)
Matrix Gla protein (MGP) is involved in calcium trafficking and arterial calcification. The aim of study was to investigate the role of three polymorphisms within the MGP gene promoter region on reporter gene (luciferase) expression level. The fragments containing rs1800799 (C/T), rs1800802 (T/C), and rs1800801 (G/A) sites were constructed and transferred(More)
Although the role of matrix Gla protein (MGP) is not completely known but, its expression within subendothelial macrophages and vascular smooth muscle cells is suggested to be involved in vascular calcification. In this study, we investigated the associations between the serum MGP levels and the MGP promoter high minor allele frequency (MAF) variants with(More)
Abstr act. Background: Matrix Gla protein (MGP) is known as a calcium scavenger within sub-endothelial space of vessels, so that its function is suggested to reduce the risk of coronary artery diseases. In this study, we predicted the role of MGP promoter rs1800801, rs1800802 and rs1800799 variants on the score changes of predicted transcription elements.(More)
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