Abas Sabouni

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The objective of this study was to investigate the role of the transfollicular pathway in the diffusion process of chemicals through excised human skin in vitro. Skin was obtained from 5 cadavers (3 males, 3 females) within 24 h of death. The age of the subjects varied between 18-77 years. Three radiolabelled drugs, namely 14C-coumarin, 3H-propranolol and(More)
Rosmarinic acid (RA) is a nonsteroidal anti-inflammatory agent. The purpose of the study was to investigate the transdermal absorption of RA, its tissue distribution and absolute bioavailability. In ex vivo experiments, permeation of RA across excised rat skin was about 8 times higher from alcoholic solution than from water, indicating that ethanol may act(More)
Breast cancer, with the exception of lung cancer, is the leading cause of cancer deaths in women. It is also one of the few cancers that can be controlled by using asymptomatic screening method, followed by effective treatments. One recent screening modality under development, microwave tomography, uses the apparent dielectric property contrasts between(More)
Breast cancer incidence in women has increased from one in twenty in 1960 to one in eight today. Although advances have improved the likelihood of early detection, current breast imaging modalities still have limitations. In recent years, microwave imaging has shown its potential as an alternative approach for breast cancer detection. The principle behind(More)
Regularization methods are used in microwave image reconstruction problems, which are ill-posed. Traditional regularization methods are usually problem-independent and do not take advantage of a priori information specific to any particular imaging application. In this paper, a novel problem-dependent regularization approach is introduced for the(More)
This paper addresses a two-dimensional inverse scattering method with a combination of tomography and radar methods for breast cancer detection. In order to rapidly construct high resolution images displaying the location, size, permittivity and conductivity of malignant tumors inside the body, the collected reflection from the scattered fields present in(More)
In this paper, we introduced an automated TMS system with robot control and optical sensor combined with neuronavigation software. By using the robot, the TMS coil can be accurately positioned over any preselected brain region. The neuronavigation system provides an accurate positioning of a magnetic coil in order to induce a specific cortical excitation.(More)
Different technologies have been used for breast cancer detections clinically. But they have weaknesses in terms of sensitivity and specificity. Microwave imaging technique, on the contrary, uses the apparent dielectric property contrasts between different breast tissues at microwave frequencies and is a prospective direction to find small tumor at their(More)
This paper illustrates how breast tissue composition, modeled by different mixtures of adipose and glandular tissues, affects the accuracy of microwave breast imaging for different sizes of malignant lesions. To study this, the scattered field for different tissue composition and various tumour sizes was calculated using a Frequency Dependent Finite(More)
This paper introduce a fast and efficient solver for simulating the induced (eddy) current distribution in the brain during transcranial magnetic stimulation procedure. This solver has been integrated with MRI and neuronavigation software to accurately model the electromagnetic field and show eddy current in the head almost in real-time. To examine the(More)