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FlyBase (http://flybase.bio.indiana.edu/) provides an integrated view of the fundamental genomic and genetic data on the major genetic model Drosophila melanogaster and related species. FlyBase has primary responsibility for the continual reannotation of the D. melanogaster genome. The ultimate goal of the reannotation effort is to decorate the euchro-matic(More)
While it is clear that a single hematopoietic stem cell (HSC) is capable of giving rise to all other hematopoietic cell types, the differentiation paths beyond HSC remain controversial. Contradictory reports on the lineage potential of progenitor populations have questioned their physiological contribution of progenitor populations to multilineage(More)
A study group of 271 registrants had their medical and social history taken by a nurse-interviewer and were requested to take the Substance Abuse Subtle Screening Inventory. If the nurse interviewer felt that the patient needed social service assessment, referral was made, and a social worker completed the the Social Service Review Questionnaire. The(More)
Pathologic features of idiopathic pulmonary fibrosis (IPF) include genetic predisposition, activation of the unfolded protein response, telomere attrition, and cellular senescence. The mechanisms leading to alveolar epithelial cell (AEC) senescence are poorly understood. MicroRNAs (miRNAs) have been reported as regulators of cellular senescence. Senescence(More)
Research findings from the organizational theory tend to support the position that management uses Information Technology (IT) to maintain existing organizational hierachy and control. Another body of research from information technology advocates suggests that Information Technology's inherent capabilities transform organization hierarchy and control(More)
In this paper we couple a spatiotemporal air quality model of ozone concentration levels with the synthetic information model of the Houston Metropolitan Area. While traditional approaches often aggregate the population, activities, or concentration levels of the pollutant across space and/or time, we utilize high performance computing and statistical(More)
The recent paper deals with the influence of nutritional situation on the ability of cell sap fractions of liver and muscle of rats to stimulate protein biosynthesis in a cell-free system. The incorporation of 3H-leucine into polypeptides from tissues of ad libitum fed rats was 1.25-1.46 fold higher in the liver resp. 1.2-1.7 fold higher in the muscle in(More)
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