Aaron R Morawski

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Abbreviations EBNA Epstein–Barr nuclear antigen EBV Epstein–Barr virus HE Hematoxylin eosin HHV-8 Human herpes virus 8 HIV Human immunodeficiency virus IVIG Intravenous immunoglobulin KS Kaposi Sarcoma MFI Mean fluorescence intensity PBMC Peripheral blood mononuclear cells PID Primary immunodeficiency PLCγ1 Phospholipase C gamma 1 TCR T cell receptor WES(More)
Members of the miR-290 family are the most abundantly expressed microRNAs (miRNAs) in mouse embryonic stem cells (ESCs). They regulate aspects of differentiation, pluripotency, and proliferation of ESCs, but the molecular program that they control has not been fully delineated. In the absence of Dicer, ESCs fail to express mature miR-290 miRNAs and have(More)
BACKGROUND Studies of monogenic gastrointestinal diseases have revealed molecular pathways critical to gut homeostasis and enabled the development of targeted therapies. METHODS We studied 11 patients with abdominal pain and diarrhea caused by early-onset protein-losing enteropathy with primary intestinal lymphangiectasia, edema due to hypoproteinemia,(More)
BACKGROUND Transmissible spongiform encephalopathies (TSEs) affect both domestic sheep (scrapie) and captive and free-ranging cervids (chronic wasting disease; CWD). The geographical range of bighorn sheep (Ovis canadensis; BHS) overlaps with states or provinces that have contained scrapie-positive sheep or goats and areas with present epizootics of CWD in(More)
Studies to understanding interspecies transmission of transmissible spongiform encephalopathies (TSEs, prion diseases) are challenging in that they typically rely upon lengthy and costly in vivo animal challenge studies. A number of in vitro assays have been developed to aid in measuring prion species barriers, thereby reducing animal use and providing(More)
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