Aaron R. Hawkins

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The analysis of individual biological nanoparticles has significantly advanced our understanding of fundamental biological processes but is also rapidly becoming relevant for molecular diagnostic applications in the emerging field of personalized medicine. Both optical and electrical methods for the detection and analysis of single biomolecules have been(More)
Scanning impedance imaging (SH) uses a noncontacting electrical probe held at a known voltage and scanned over a thin sample on a ground plane in a conductive medium to obtain images of current. The current image is related in a nonlinear way to the conductivity of the sample. This paper develops the theory behind SII showing how the measured current(More)
The massive outbreak of highly lethal Ebola hemorrhagic fever in West Africa illustrates the urgent need for diagnostic instruments that can identify and quantify infections rapidly, accurately, and with low complexity. Here, we report on-chip sample preparation, amplification-free detection and quantification of Ebola virus on clinical samples using hybrid(More)
Optofluidic platforms used for biomolecular detection require spectral filtering for distinguishing analyte signals from unwanted background. Towards a fully integrated platform, an on-chip filter is required. Selective deposition of dielectric thin films on an optofluidic sensor based on antiresonant reflecting optical waveguide (ARROW) technology provides(More)
The final copy of this thesis has been examined by the signatories, and we find that both the content and the form meet acceptable presentation standards of scholarly work in the above mentioned discipline Thesis directed by Prof. Garret Moddel Optical rectennas, which are micro-antennas to convert optical-frequency radiation to alternating current combined(More)
Microcantilevers have been investigated as high sensitivity, label free biosensors for approximately 15 years. In nearly all cases, a thin gold film deposited on the microcantilevers is used as an intermediate attachment layer because of the convenience of thiol-gold chemistry. Unfortunately, this attachment chemistry can be unstable when used with complex(More)
  • Jong Wook Noh, Gregory P Nordin, Brian D Jensen, Aaron R Hawkins, Stephen M Schultz, Richard H Selfridge +4 others
  • 2009
Doctor of Philosophy We have invented an in-plane all-photonic transduction method for photonic microcantilever arrays that is scalable to large arrays for sensing applications in both bio-and nanotechnology. Our photonic transduction method utilizes a microcantilever forming a single mode rib waveguide and a differential splitter consisting of an(More)
Scanning (electrical) impedance imaging (SII) is a novel high-resolution imaging modality that has the potential of imaging the electrical properties of thin biological tissues. In this paper, we apply the reciprocity principle to the modeling of the SII system and develop a fast nonlinear inverse method for image reconstruction. The method is fast because(More)