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- Oswald Quehenberger, Aaron M. Armando, +21 authors Edward A. Dennis
- Journal of lipid research
- 2010
The focus of the present study was to define the human plasma lipidome and to establish novel analytical methodologies to quantify the large spectrum of plasma lipids. Partial lipid analysis is now a… (More)
- Da Young Oh, Evelyn Walenta, +18 authors Jerrold M. Olefsky
- Nature Medicine
- 2014
It is well known that the ω–3 fatty acids (ω–3-FAs; also known as n–3 fatty acids) can exert potent anti-inflammatory effects. Commonly consumed as fish products, dietary supplements and… (More)
- Oswald Quehenberger, Aaron M. Armando, Edward A. Dennis
- Biochimica et biophysica acta
- 2011
Historically considered to be simple membrane components serving as structural elements and energy storing entities, fatty acids are now increasingly recognized as potent signaling molecules involved… (More)
- Yanli Wang, Aaron M. Armando, Oswald Quehenberger, Chao Yan, Edward A. Dennis
- Journal of chromatography. A
- 2014
Over the past decade, the number of known eicosanoids has expanded immensely and we have now developed an ultra-performance liquid chromatography-electrospray ionization triple quadrupole mass… (More)
- António Currais, Marguerite Prior, +5 authors Pamela A. Maher
- Aging cell
- 2014
Alzheimer's disease (AD) is the most common type of dementia. It is the only one of the top ten causes of death in the USA for which prevention strategies have not been developed. Although AD has… (More)
- Andrew M. F. Johnson, Anne E. Costanzo, +4 authors Jerrold M. Olefsky
- PloS one
- 2015
The development of intestinal permeability and the penetration of microbial products are key factors associated with the onset of metabolic disease. However, the mechanisms underlying this remain… (More)
- David Lee Gorden, David S. Myers, +30 authors Haley A Brown
- Journal of lipid research
- 2015
The spectrum of nonalcoholic fatty liver disease (NAFLD) includes steatosis, nonalcoholic steatohepatitis (NASH), and cirrhosis. Recognition and timely diagnosis of these different stages,… (More)
- R Loomba, Oswald Quehenberger, Aaron M. Armando, Edward A. Dennis
- Journal of lipid research
- 2015
Lipotoxicity is a key mechanism thought to be responsible for the progression of nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH). Noninvasive diagnosis of NASH is a major unmet… (More)
NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids
- Pingping Li, Nathanael J. Spann, +15 authors Jerrold M. Olefsky
- Cell
- 2013
Macrophage-mediated inflammation is a major contributor to obesity-associated insulin resistance. The corepressor NCoR interacts with inflammatory pathway genes in macrophages, suggesting that its… (More)
- S Choi, Huiyong Yin, +10 authors Yury I. Miller
- PloS one
- 2013
Oxidation of low-density lipoprotein (LDL) is one of the major causative mechanisms in the development of atherosclerosis. In previous studies, we showed that minimally oxidized LDL (mmLDL) induced… (More)