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A wearable cardiopulmonary monitoring system, a LifeShirt, was used to acquire continuous electrocardiograms (ECGs) from ambulatory swine. The animals received intracoronary injections of autologous mesenchymal stem cells, and the LifeShirt was used for long-duration ECG monitoring in pre-defined periods post cell infusion. The system used here was(More)
OBJECTIVES The potential for beneficial effects of adipose-derived stem cells (ASCs) on myocardial perfusion and left ventricular dysfunction in myocardial ischemia (MI) has not been tested following intravenous delivery. METHODS Surviving pigs following induction of MI were randomly assigned to 1 of 3 different groups: the placebo group (n = 7), the(More)
The efficacy of an acoustic transmission line model (TLM) for predicting distortion that occurs with axial propagation in liquid-filled arterial segments was assessed. Water-filled segments of excised bovine aorta were excited with acoustic pulses and noise to evaluate if velocities, attenuation, and transverse resonance frequencies could be accurately(More)
We propose the use of gallium (Ga), a metal that is liquid at physiological temperatures, or one of its alloys, for use as the conducting material in the leads of implantable pacemakers or cardioverter defibrillators. It is proposed that a liquid conductor will make these leads more pliable and thus less susceptible to fracture in situ. As an initial step(More)
We have developed a bioinstrumentation course that emphasizes practical application of engineering and biological concepts by having students focus on the development of a single biomedical device: a cardiac pacemaker. In creating their benchtop pacemaker, students learn about and design sensing circuitry, data acquisition and processing code, control(More)
A computer tool, based on an acoustic transmission line model, was developed for modeling and predicting sound propagation and reflections in cascaded tube segments. This subroutine considered the number of interconnected tubes, their dimensions and wall properties, as well as medium properties to create a network of cascaded transmission line model(More)
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