Aaron Leong

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Effective management of populations with asthma requires methods for identifying patients at high risk for adverse outcomes. The aim of this study was to develop and validate prediction models that used computerized utilization data from a large health-maintenance organization (HMO) to predict asthma-related hospitalization and emergency department (ED)(More)
OBJECTIVES Health administrative data are frequently used for diabetes surveillance. We aimed to determine the sensitivity and specificity of a commonly-used diabetes case definition (two physician claims or one hospital discharge abstract record within a two-year period) and their potential effect on prevalence estimation. METHODS Following Preferred(More)
OBJECTIVE We performed a qualitative study among women within 5 years of Gestational Diabetes (GDM) diagnosis. Our aim was to identify the key elements that would enhance participation in a type 2 diabetes (DM2) prevention program. RESEARCH DESIGN AND METHODS Potential participants received up to three invitation letters from their GDM physician. Four(More)
BACKGROUND Diabetes history in biologically-related individuals increases diabetes risk. We assessed diabetes concordance in spouses (that is, biologically unrelated family members) to gauge the importance of socioenvironmental factors. METHODS We selected cross-sectional, case-control and cohort studies examining spousal association for diabetes and/or(More)
OBJECTIVE Health administrative data are frequently used for diabetes surveillance, but validation studies are limited, and undiagnosed diabetes has not been considered in previous studies. We compared the test properties of an administrative definition with self-reported diabetes and estimated prevalence of undiagnosed diabetes by measuring glucose levels(More)
  • Aaron Leong
  • 2007
BIOCHEMISTRY AND NATURAL HISTORY OF G6PD DEFICIENCY G6PD is an enzyme in the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells, in particular erythrocytes, by maintaining the level of nicotinamide adenine dinucleotide phosphate (NADPH). NADPH in turn maintains the level of glutathione that helps protect erythrocytes(More)
  • Aaron Leong
  • 2006
INTRODUCTION Sexual dimorphism of the human pelvis is linked intimately with its adaptive functions. The peculiarly shaped hominid pelvis represents the total response to the diverse forces that have moulded its structure. These diverse forces are requirements for efficient bipedalism and parturition. In some respects, the structural demands of these(More)
BACKGROUND Women with gestational diabetes history are at increased risk for type 2 diabetes. They face specific challenges for behavioural changes, including childcare responsibilities. The aim of this study is to test a tailored type 2 diabetes prevention intervention in women within 5 years of a pregnancy with gestational diabetes, in terms of effects on(More)
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