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  • Kewei Ma, Samuel M Cheung, Aaron J Marshall, Vincent Duronio
  • Biology, Medicine
  • Cellular signalling
  • 2008 (First Publication: 1 April 2008)
  • The PI3K-PKB pathway is an important and widely studied pathway in cell signaling. The enzyme activity of PI3K produces D-3 phosphoinositides, including the lipid second messengers PI(3,4,5)P3 andExpand
  • Dong Xiang Liu, Tingting Christina Zhang, Aaron J Marshall, Klaus Okkenhaug, Bart Vanhaesebroeck, Jude E. Uzonna
  • Medicine, Biology
  • The Journal of Immunology
  • 2009 (First Publication: 1 August 2009)
  • Resistance to Leishmania major and most intracellular pathogens is usually associated with a strong T cell-mediated immunity, particularly a CD4+ Th1 response. Mice with an inactivating knock-inExpand
  • Aaron J Marshall, Allyson K Krahn, Kewei Ma, Vincent Duronio, Sen Hou
  • Medicine, Biology
  • Molecular and Cellular Biology
  • 2002 (First Publication: 1 August 2002)
  • ABSTRACT We report the characterization of two signal transduction proteins related to Bam32, known as TAPP1 and TAPP2. Bam32, TAPP1, and TAPP2 share several characteristics, including small size (32Expand
  • Aaron J Marshall, Hiroaki Niiro, +4 authors Edward A Clark
  • Medicine, Biology
  • The Journal of experimental medicine
  • 2000 (First Publication: 17 April 2000)
  • We have identified and characterized a novel src homology 2 (SH2) and pleckstrin homology (PH) domain–containing adaptor protein, designated Bam32 (for B cell adaptor molecule of 32 kD). cDNAsExpand
    The induction of a type 1 inflammatory cytokine response is a key event in the initiation of immunity to Toxoplasma gondii. Because polymorphonuclear leukocytes rapidly respond to infection byExpand
  • Baher F. Nashed, Tingting Christina Zhang, +6 authors Aaron J Marshall
  • Medicine
  • European journal of immunology
  • 2007 (First Publication: 1 February 2007)
  • Phosphoinositide 3-kinases (PI3K) regulate immune activation via their roles in signal transduction of multiple classes of receptors. Here, we examined the effect of genetic inactivation of theExpand
  • Aaron J Marshall, Heather E. Fleming, Gillian E. Wu, Christopher J Paige
  • Biology, Medicine
  • Journal of immunology
  • 1998 (First Publication: 1 December 1998)
  • The IL-7R and the pre-B cell receptor (pre-BCR) each provide critical signals during differentiation of B cell precursors. In this study we examine the interplay between signals dependent upon theseExpand